Research
Our research focus is on developing computational tools for analysis of single-cell RNA sequencing and multimodal data types and applying these tools for improved understanding of tumor immunotherapy resistance mechanisms. With multiple mechanisms of treatment resistance present to varying degreees across tumor types and across patients, it is critical to understand tumor immune interactions within the microenvironment of solid tumors and develop a rational approach to combination therapy in treatment-resistant individuals.
2023
Science · 16 Feb 2023
Cold Spring Harbor Laboratory · 02 Jan 2023
2022
European Urology · 13 Sep 2022
Clinical Cancer Research · 15 May 2022
Cold Spring Harbor Laboratory · 09 May 2022
Cold Spring Harbor Laboratory · 02 Mar 2022
Cold Spring Harbor Laboratory · 23 Feb 2022
Cold Spring Harbor Laboratory · 25 Jan 2022
2021
The Journal of Pathology · 03 Nov 2021
Nature Cancer · 19 Jul 2021
Journal for ImmunoTherapy of Cancer · 30 Jun 2021
Cancer Immunology Research · 01 May 2021
Journal of Clinical Investigation · 25 Feb 2021
Clinical Cancer Research · 19 Jan 2021
2020
American Journal of Transplantation · 05 Oct 2020
Clinical Cancer Research · 01 Jul 2020
2019
Journal for ImmunoTherapy of Cancer · 01 Oct 2019
American Journal of Transplantation · 18 Jul 2019
Journal of Clinical Investigation · 28 Mar 2019
2018
JCI Insight · 01 Nov 2018
JCI Insight · 09 Aug 2018
2017
American Journal of Transplantation · 01 Mar 2017
2016
Science Immunology · 01 Oct 2016